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Indicated for: Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome (as adjunctive therapy to continuous positive airway pressure), Shift Work Sleep Disorder, Headache, Nausea, Anxiety, Dizziness, Insomnia, Diarrhea.
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United States clinical practice guidelines developed by the American Academy of Sleep Medicine provide strong recommendations for the use of MODALERT in narcolepsy and Shift Work Sleep Disorder based on high-quality evidence, with similarly favorable recommendations for adjunctive use in Obstructive Sleep Apnea/Hypopnea Syndrome with residual sleepiness despite optimal continuous positive airway pressure therapy. Australian patients are counseled that while MODALERT can be taken with or without food, establishing a consistent routine is essential for maintaining stable plasma concentrations and predictable therapeutic response across days and weeks of therapy. The safety concerns that emerged from pediatric modafinil ADHD trials are particularly relevant to any consideration of using MODALERT 200 mg for this condition, as the risk of serious cutaneous adverse reactions appears to be higher in pediatric populations and with the higher doses sometimes used in ADHD studies.
Can Accutane Prescriptions Be Transferred Between Pharmacies. The Australian experience confirms that patients who experience subjective improvement in mood and anxiety during MODALERT therapy require ongoing monitoring for recurrence of psychiatric symptoms should MODALERT be discontinued or should its wakefulness-promoting efficacy diminish over time.
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